COB may refer to any of the following:
Short for chip on board, COB is a system where semiconductor dice are mounted directly on a PC board and connected with either bonded wires or solder bumps.
Abbreviation for close of business, COB is a deadline or time. For example, a co-worker may send you an e-mail saying they need to have work done by COB.
Business terms, Computer acronyms, EOD